Asymmetric Dimethylarginine and Hypertension in Carotid Artery Disease | Zendy

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Asymmetric Dimethylarginine and Hypertension in Carotid Artery Disease

Author(s) -

Kazushi Tsuda

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.563973

Subject(s) - medicine , asymmetric dimethylarginine , cardiology , common carotid artery , endothelial dysfunction , blood pressure , intima media thickness , carotid artery disease , subclinical infection , essential hypertension , carotid arteries , carotid endarterectomy , arginine , biochemistry , chemistry , amino acid

To the Editor:We read with great interest the recent article by Maas and colleagues1 dealing with the relationships between endogenous nitric oxide (NO) synthase inhibitor, asymmetrical dimethylarginine (ADMA), and carotid artery intimal media thickness. The results of their study demonstrated that higher plasma concentrations of ADMA were associated with greater internal carotid artery/bulb intima media thickness but not with greater common carotid artery intima media thickness in a large community-based sample. The authors proposed that ADMA might promote subclinical atherosclerosis in a site-specific manner and serve as …

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