Effects of Perindopril-Based Lowering of Blood Pressure on Intracerebral Hemorrhage Related to Amyloid Angiopathy
Author(s) -
Hisatomi Arima,
Christophe Tzourio,
Craig S. Anderson,
Mark Woodward,
M G Bousser,
Stephen MacMahon,
Bruce Neal,
John Chalmers
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.109.563932
Subject(s) - medicine , cerebral amyloid angiopathy , intracerebral hemorrhage , indapamide , contraindication , perindopril , blood pressure , placebo , stroke (engine) , randomized controlled trial , cardiology , disease , dementia , subarachnoid hemorrhage , pathology , mechanical engineering , alternative medicine , engineering
Patients with cerebral amyloid angiopathy (CAA) are at high risk for intracerebral hemorrhage (ICH), but no effective prevention strategies have been established. The objective is to determine whether lowering of blood pressure (BP) provides protection for this high-risk patient group.
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