Postthrombolysis Blood Pressure Elevation Is Associated With Hemorrhagic Transformation | Zendy

Kenneth Butcher | Zendy; Sören Christensen | Zendy; Mark Parsons | Zendy; Deidre Anne De Silva | Zendy; Martin Ebinger | Zendy; Christopher Levi | Zendy; Thomas Jeerakathil | Zendy; Bruce Campbell | Zendy; P. Alan Barber | Zendy; Christopher Bladin | Zendy; John Fink | Zendy; Brian Tress | Zendy; Geoffrey A. Donnan | Zendy; Stephen M. Davis | Zendy

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Postthrombolysis Blood Pressure Elevation Is Associated With Hemorrhagic Transformation

Author(s) -

Kenneth Butcher,

Sören Christensen,

Mark Parsons,

Deidre Anne De Silva,

Martin Ebinger,

Christopher Levi,

Thomas Jeerakathil,

Bruce Campbell,

P. Alan Barber,

Christopher Bladin,

John Fink,

Brian Tress,

Geoffrey A. Donnan,

Stephen M. Davis

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.563767

Subject(s) - medicine , odds ratio , intracerebral hemorrhage , thrombolysis , placebo , blood pressure , stroke (engine) , lesion , hematoma , tissue plasminogen activator , cardiology , anesthesia , surgery , myocardial infarction , pathology , subarachnoid hemorrhage , mechanical engineering , alternative medicine , engineering

Reliable predictors of hemorrhagic transformation (HT) after stroke thrombolysis have not been identified. We analyzed hemorrhage in a randomized trial of tissue plasminogen activator (t-PA) vs placebo in ischemic stroke patients. We hypothesized that acute diffusion-weighted imaging (DWI) lesion volumes would be larger and blood pressures would be higher in patients with HT.

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