Electrical Stimulation of the Cerebral Cortex Exerts Antiapoptotic, Angiogenic, and Anti-Inflammatory Effects in Ischemic Stroke Rats Through Phosphoinositide 3-Kinase/Akt Signaling Pathway
Author(s) -
Tanefumi Baba,
Masahiro Kameda,
Takao Yasuhara,
Takamasa Morimoto,
Akihiko Kondo,
Tetsuro Shingo,
Naoki Tajiri,
Feifei Wang,
Yasuyuki Miyoshi,
Cesar V. Borlongan,
Mitsunori Matsumae,
Isao Date
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.109.563627
Subject(s) - medicine , neurotrophic factors , ly294002 , stimulation , angiogenesis , phosphoinositide 3 kinase , neuroprotection , pi3k/akt/mtor pathway , neuroscience , neurotrophin , protein kinase b , ischemia , cerebral cortex , brain derived neurotrophic factor , endocrinology , signal transduction , pharmacology , microbiology and biotechnology , biology , receptor
Neuroprotective effects of electric stimulation have been recently shown in ischemic stroke, but the underlying mechanisms remain poorly understood.
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