Hyperlipidemia and Reduced White Matter Hyperintensity Volume in Patients With Ischemic Stroke | Zendy

Jordi Jiménez-Conde | Zendy; Alessandro Biffi | Zendy; Rosanna Rahman | Zendy; Allison Kanakis | Zendy; Christi Butler | Zendy; Shruti Sonni | Zendy; Efi E. Massasa | Zendy; Lisa Cloonan | Zendy; Aaron J. Gilson | Zendy; Karen Capozzo | Zendy; Lynelle Cortellini | Zendy; Ángel Ois | Zendy; Elisa CuadradoGodia | Zendy; Ana Rodríguez-Campello | Zendy; Karen L. Furie | Zendy; Jaume Roquer | Zendy; Jonathan Rosand | Zendy; Natalia S. Rost | Zendy

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Hyperlipidemia and Reduced White Matter Hyperintensity Volume in Patients With Ischemic Stroke

Author(s) -

Jordi Jiménez-Conde,

Alessandro Biffi,

Rosanna Rahman,

Allison Kanakis,

Christi Butler,

Shruti Sonni,

Efi E. Massasa,

Lisa Cloonan,

Aaron J. Gilson,

Karen Capozzo,

Lynelle Cortellini,

Ángel Ois,

Elisa CuadradoGodia,

Ana Rodríguez-Campello,

Karen L. Furie,

Jaume Roquer,

Jonathan Rosand,

Natalia S. Rost

Publication year - 2010

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.563502

Subject(s) - medicine , hyperintensity , stroke (engine) , hyperlipidemia , cardiology , ischemic stroke , leukoaraiosis , magnetic resonance imaging , ischemia , radiology , diabetes mellitus , endocrinology , engineering , mechanical engineering

White matter hyperintensity (WMH), or leukoaraiosis, is a radiologic finding generally assumed to reflect diseased small cerebral vasculature. WMH has significant functional impact through its relation to cognitive decline and risk of ischemic and hemorrhagic stroke. Accumulating evidence suggests that some manifestations of small-vessel disease such as intracerebral hemorrhage are associated with low levels of cholesterol. We sought to determine the relation between hyperlipidemia and WMH severity in patients with acute ischemic stroke (AIS).

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