The Benefits of Intravenous Thrombolysis Relate to the Site of Baseline Arterial Occlusion in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET)
Author(s) -
Deidre Anne De Silva,
Caspar Brekenfeld,
Martin Ebinger,
Sören Christensen,
P. Alan Barber,
Kenneth Butcher,
Christopher Levi,
Mark Parsons,
Christopher F. Bladin,
Geoffrey A. Donnan,
Stephen M. Davis
Publication year - 2010
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.109.562827
Subject(s) - medicine , thrombolysis , placebo , fibrinolytic agent , middle cerebral artery , randomized controlled trial , stroke (engine) , angiography , surgery , tissue plasminogen activator , cardiology , radiology , ischemia , myocardial infarction , pathology , mechanical engineering , alternative medicine , engineering
In ischemic stroke, the site of arterial obstruction has been shown to influence recanalization and clinical outcomes. However, this has not been studied in randomized controlled trials, nor has the impact of arterial obstruction site on reperfusion and infarct growth been assessed. We studied the influence of site and degree of arterial obstruction patients enrolled in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET).
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