Increased Risk of Stroke After a Herpes Zoster Attack | Zendy

JiunnHorng Kang | Zendy; JauDer Ho | Zendy; YiHua Chen | Zendy; HerngChing Lin | Zendy

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Increased Risk of Stroke After a Herpes Zoster Attack

Author(s) -

JiunnHorng Kang,

JauDer Ho,

YiHua Chen,

HerngChing Lin

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.562017

Subject(s) - medicine , stroke (engine) , cohort , herpes zoster ophthalmicus , hazard ratio , attack rate , varicella zoster virus , proportional hazards model , population , cohort study , retrospective cohort study , confounding , shingles , surgery , pediatrics , epidemiology , confidence interval , virus , immunology , mechanical engineering , environmental health , engineering

Varicella zoster virus-induced vasculopathy and postherpes zoster attack stroke syndromes have been reported previously; nevertheless, data regarding the exact prevalence and risk of stroke occurring postherpes zoster attack are still lacking. This study aims to investigate the frequency and risk of stroke after a herpes zoster attack using a nationwide, population-based study of a retrospective cohort design. Method- A total of 7760 patients who had received treatment for herpes zoster between 1997 and 2001 were included and matched with 23 280 randomly selected subjects. A 1-year stroke-free survival rate was then estimated using the Kaplan-Meier method. After adjusting for potential confounders, Cox proportional hazard regressions were carried out to compute the adjusted 1-year survival rate.

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