Hypertonic Saline In Patients With Poor-Grade Subarachnoid Hemorrhage Improves Cerebral Blood Flow, Brain Tissue Oxygen, and pH | Zendy

Pippa G. Al-Rawi | Zendy; Ming-Yuan Tseng | Zendy; Hugh K. Richards | Zendy; Jürgens Nortje | Zendy; Ivan Timofeev | Zendy; Basil Matta | Zendy; Peter J. Hutchinson | Zendy; Peter J. Kirkpatrick | Zendy

Open Access

Hypertonic Saline In Patients With Poor-Grade Subarachnoid Hemorrhage Improves Cerebral Blood Flow, Brain Tissue Oxygen, and pH

Author(s) -

Pippa G. Al-Rawi,

Ming-Yuan Tseng,

Hugh K. Richards,

Jürgens Nortje,

Ivan Timofeev,

Basil Matta,

Peter J. Hutchinson,

Peter J. Kirkpatrick

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.560698

Subject(s) - medicine , subarachnoid hemorrhage , cerebral blood flow , intracranial pressure , anesthesia , cerebral perfusion pressure , oxygenation , hypertonic saline , ischemia , perfusion , brain tissue , hemodynamics , blood flow , blood pressure , mean arterial pressure , middle cerebral artery , cardiology , heart rate

Delayed cerebral ischemia and infarction due to reduced CBF remains the leading cause of poor outcome after aneurysmal subarachnoid hemorrhage. Hypertonic saline (HS) is associated with an increase in CBF. This study explores whether CBF enhancement with HS in patients with poor-grade subarachnoid hemorrhage is associated with improved cerebral tissue oxygenation.

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