Reliable Perfusion Maps in Stroke MRI Using Arterial Input Functions Derived From Distal Middle Cerebral Artery Branches | Zendy

Martin Ebinger | Zendy; Peter Brunecker | Zendy; Gerhard J. Jungehülsing | Zendy; Uwe Malzahn | Zendy; Claudia Kunze | Zendy; Matthias Endres | Zendy; Jochen B. Fiebach | Zendy

Open Access

Reliable Perfusion Maps in Stroke MRI Using Arterial Input Functions Derived From Distal Middle Cerebral Artery Branches

Author(s) -

Martin Ebinger,

Peter Brunecker,

Gerhard J. Jungehülsing,

Uwe Malzahn,

Claudia Kunze,

Matthias Endres,

Jochen B. Fiebach

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.559807

Subject(s) - medicine , middle cerebral artery , interquartile range , perfusion scanning , nuclear medicine , bolus (digestion) , stroke (engine) , perfusion , radiology , cardiology , ischemia , mechanical engineering , engineering

Perfusion imaging is widely used in stroke, but there are uncertainties with regard to the choice of arterial input function (AIF). Two important aspects of AIFs are signal-to-noise ratio and bolus-related signal drop, ideally close to 63%. We hypothesized that distal branches of the middle cerebral artery (MCA) provide higher quality of AIF compared with proximal branches.

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