Differences in the Evolution of the Ischemic Penumbra in Stroke-Prone Spontaneously Hypertensive and Wistar-Kyoto Rats | Zendy

Christopher McCabe | Zendy; Lindsay Gallagher | Zendy; Willy Gsell | Zendy; Delyth Graham | Zendy; Anna F. Dominiczak | Zendy; I. Mhairi Macrae | Zendy

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Differences in the Evolution of the Ischemic Penumbra in Stroke-Prone Spontaneously Hypertensive and Wistar-Kyoto Rats

Author(s) -

Christopher McCabe,

Lindsay Gallagher,

Willy Gsell,

Delyth Graham,

Anna F. Dominiczak,

I. Mhairi Macrae

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.559021

Subject(s) - penumbra , medicine , stroke (engine) , ischemia , lesion , perfusion , magnetic resonance imaging , middle cerebral artery , ischemic stroke , cardiology , nuclear medicine , pathology , radiology , mechanical engineering , engineering

Stroke-prone spontaneously hypertensive rats (SHRSP) are a highly pertinent stroke model with increased sensitivity to focal ischemia compared with the normotensive reference strain (Wistar-Kyoto rats; WKY). Study aims were to investigate temporal changes in the ischemic penumbra in SHRSP compared with WKY.

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