Sites of Rupture in Human Atherosclerotic Carotid Plaques Are Associated With High Structural Stresses
Author(s) -
Dalin Tang,
Zhongzhao Teng,
Gádor Cantón,
Chun Yang,
Marina S. Ferguson,
Xueying Huang,
Jie Zheng,
Pamela K. Woodard,
Chun Yuan
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.109.558676
Subject(s) - medicine , carotid endarterectomy , endarterectomy , pathology , lumen (anatomy) , radiology , carotid arteries , cardiology
It has been hypothesized that high structural stress in atherosclerotic plaques at critical sites may contribute to plaque disruption. To test that hypothesis, 3D fluid-structure interaction models were constructed based on in vivo MRI data of human atherosclerotic carotid plaques to assess structural stress behaviors of plaques with and without rupture.
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