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To the Editor:We read with interest the article by Kim and colleagues1 reporting on the effect of low level of total cholesterol and low low-density lipoprotein cholesterol (LDLC) on hemorrhagic transformation (HT) after acute ischemic stroke. The authors found that low levels of LDLC are independently associated with the risk of HT after acute ischemic stroke attributable to large artery atherothrombosis (LAA) but not to cardioembolism (CE). The authors commented on the results saying that they should be interpreted with caution in consideration of several points: …

Low Levels of Low-Density Lipoprotein Cholesterol Increase Hemorrhagic Transformation but Not Parenchimal Hematoma in Large Artery Atherothrombosisis