Intense Correlation Between Brain Infarction and Protein-Conjugated Acrolein | Zendy

Ryotaro Saiki | Zendy; Kazuhiro Nishimura | Zendy; Itsuko Ishii | Zendy; Tomohiro Omura | Zendy; Shigeru Okuyama | Zendy; Keiko Kashiwagi | Zendy; Kazuei Igarashi | Zendy

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Intense Correlation Between Brain Infarction and Protein-Conjugated Acrolein

Author(s) -

Ryotaro Saiki,

Kazuhiro Nishimura,

Itsuko Ishii,

Tomohiro Omura,

Shigeru Okuyama,

Keiko Kashiwagi,

Kazuei Igarashi

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.553248

Subject(s) - acrolein , spermine , spermidine , polyamine , infarction , medicine , cerebral infarction , biochemistry , microbiology and biotechnology , myocardial infarction , chemistry , enzyme , biology , ischemia , catalysis

We recently found that increases in plasma levels of protein-conjugated acrolein and polyamine oxidases, enzymes that produce acrolein, are good markers for stroke. The aim of this study was to determine whether the level of protein-conjugated acrolein is increased and levels of spermine and spermidine, the substrates of acrolein production, are decreased at the locus of infarction.

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