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Cryptogenic Stroke and Patent Foramen Ovale: Matched Cohorts in Observational Studies Remain Matched
Author(s) -
David HildickSmith,
Bernhard Meier
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.109.552638
Subject(s) - patent foramen ovale , medicine , observational study , stroke (engine) , cohort , cohort study , population , pediatrics , surgery , migraine , mechanical engineering , environmental health , engineering
To the Editor:Serena et al1 are to be congratulated on a comprehensively and carefully conducted trial of the incidence of stroke recurrence in cryptogenic stroke patients with and without patent foramen ovale (PFO). The study showed equal recurrent stroke rates at 2-years follow-up (≈6% in each group).Unfortunately, however, the conclusion they draw from their study, that patent foramen ovale is not a risk factor …

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