The 1425G/A SNP in PRKCH Is Associated With Ischemic Stroke and Cerebral Hemorrhage in a Chinese Population | Zendy

Lijun Wu | Zendy; Yue Shen | Zendy; Xin Liu | Zendy; Xu Ma | Zendy; Bo Xi | Zendy; Jie Mi | Zendy; Klaus Lindpaintner | Zendy; Xuerui Tan | Zendy; Xingyu Wang | Zendy

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The 1425G/A SNP in PRKCH Is Associated With Ischemic Stroke and Cerebral Hemorrhage in a Chinese Population

Author(s) -

Lijun Wu,

Yue Shen,

Xin Liu,

Xu Ma,

Bo Xi,

Jie Mi,

Klaus Lindpaintner,

Xuerui Tan,

Xingyu Wang

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.551747

Subject(s) - medicine , odds ratio , snp , stroke (engine) , ischemic stroke , confidence interval , chinese population , pathogenesis , intracerebral hemorrhage , population , single nucleotide polymorphism , cardiology , gastroenterology , ischemia , genotype , subarachnoid hemorrhage , gene , genetics , biology , mechanical engineering , environmental health , engineering

PRKCH (the gene encoding protein kinase C eta) has a role in the pathogenesis of ischemic stroke. The 1425G/A SNP in PRKCH (rs2230500) is significantly associated with ischemic stroke in Japanese. The aim of the present study is to investigate the associations in ischemic stroke and other types of stroke in the Chinese population.

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