Consequences of Intraventricular Hemorrhage in a Rabbit Pup Model | Zendy

Caroline Chua | Zendy; Halima Chahboune | Zendy; Alex Braun | Zendy; Krishna Dummula | Zendy; Charles Edrick Chua | Zendy; Jen Yu | Zendy; Zoltán Ungvári | Zendy; Ariel A. Sherbany | Zendy; Fahmeed Hyder | Zendy; Praveen Ballabh | Zendy

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Consequences of Intraventricular Hemorrhage in a Rabbit Pup Model

Author(s) -

Caroline Chua,

Halima Chahboune,

Alex Braun,

Krishna Dummula,

Charles Edrick Chua,

Jen Yu,

Zoltán Ungvári,

Ariel A. Sherbany,

Fahmeed Hyder,

Praveen Ballabh

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.549212

Subject(s) - medicine , intraventricular hemorrhage , anesthesia , pregnancy , gestational age , genetics , biology

Intraventricular hemorrhage (IVH) is a common complication of prematurity that results in neurological sequelae, including cerebral palsy, posthemorrhagic hydrocephalus, and cognitive deficits. Despite this, there is no standardized animal model exhibiting neurological consequences of IVH in prematurely delivered animals. We asked whether induction of moderate-to-severe IVH in premature rabbit pups would produce long-term sequelae of cerebral palsy, posthemorrhagic hydrocephalus, reduced myelination, and gliosis.

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