Coated-Platelet Levels Are Low in Patients With Spontaneous Intracerebral Hemorrhage | Zendy

Călin I. Prodan | Zendy; Andrea S. Vincent | Zendy; Rajiv Padmanabhan | Zendy; George L. Dale | Zendy

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Coated-Platelet Levels Are Low in Patients With Spontaneous Intracerebral Hemorrhage

Author(s) -

Călin I. Prodan,

Andrea S. Vincent,

Rajiv Padmanabhan,

George L. Dale

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.549014

Subject(s) - medicine , platelet , intracerebral hemorrhage , thrombin , stimulation , platelet activation , agonist , stroke (engine) , gastroenterology , anesthesia , receptor , mechanical engineering , subarachnoid hemorrhage , engineering

Coated-platelets are a subset of platelets with high procoagulant potential observed on dual agonist stimulation with collagen and thrombin. Failure to produce coated-platelets in animals results in a bleeding diathesis. With this background, we undertook a pilot study to investigate coated-platelet production in patients with spontaneous intracerebral hemorrhage (SICH).

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