Clinical–Diffusion Mismatch and Benefit From Thrombolysis 3 to 6 Hours After Acute Stroke | Zendy

Martin Ebinger | Zendy; Takeshi Iwanaga | Zendy; Jane Prosser | Zendy; Deidre Anne De Silva | Zendy; Hanne Christensen | Zendy; Marnie Collins | Zendy; Mark Parsons | Zendy; Christopher Levi | Zendy; Christopher F. Bladin | Zendy; P. Alan Barber | Zendy; Geoffrey A. Donnan | Zendy; Stephen M. Davis | Zendy

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Clinical–Diffusion Mismatch and Benefit From Thrombolysis 3 to 6 Hours After Acute Stroke

Author(s) -

Martin Ebinger,

Takeshi Iwanaga,

Jane Prosser,

Deidre Anne De Silva,

Hanne Christensen,

Marnie Collins,

Mark Parsons,

Christopher Levi,

Christopher F. Bladin,

P. Alan Barber,

Geoffrey A. Donnan,

Stephen M. Davis

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.109.548073

Subject(s) - medicine , thrombolysis , stroke (engine) , perfusion scanning , perfusion , placebo , cardiology , anesthesia , pathology , myocardial infarction , mechanical engineering , alternative medicine , engineering

The clinical-diffusion mismatch (CDM) model has been proposed as a simpler tool than perfusion-diffusion mismatch (PDM) to select acute ischemic stroke patients for thrombolytic therapy. We hypothesized that in the 3- to 6-hour time window, the effect of tPA was significantly greater in patients with CDM than in patients without CDM.

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