Higher Systolic Blood Pressure Is Associated With Increased Water Diffusivity in Normal-Appearing White Matter
Author(s) -
Alasdair M. J. MacLullich,
Karen Ferguson,
Louise M. Reid,
Ian J. Deary,
John M. Starr,
Jonathan R. Seckl,
Mark E. Bastin,
Joanna M. Wardlaw
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.109.547877
Subject(s) - fractional anisotropy , white matter , medicine , diffusion mri , blood pressure , corpus callosum , diastole , cardiology , nuclear magnetic resonance , magnetic resonance imaging , pathology , physics , radiology
Hypertension is associated with the development of white matter lesions in older people. Diffusion tensor MRI can detect subtle, previsible white matter damage, but relationships between diffusion tensor MRI parameters and blood pressure (BP) remain unclear. We examined correlations among mean diffusivity (MD), fractional anisotropy and BP in 45 men aged 71 to 76 years.
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