Mitochondrial Targets for Stroke | Zendy

Peter S. Vosler | Zendy; Steven H. Graham | Zendy; Lawrence R. Wechsler | Zendy; Jun Chen | Zendy

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Mitochondrial Targets for Stroke

Author(s) -

Peter S. Vosler,

Steven H. Graham,

Lawrence R. Wechsler,

Jun Chen

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.543769

Subject(s) - autophagy , neuroprotection , medicine , mitochondrial biogenesis , stroke (engine) , neuroscience , mitochondrion , signal transduction , programmed cell death , bioinformatics , cause of death , microbiology and biotechnology , apoptosis , pharmacology , pathology , biology , disease , genetics , mechanical engineering , engineering

Stroke is a major cause of death and disability, and it is imperative to develop therapeutics to mitigate stroke-related injury. Despite many promising prospects, attempts at translating neuroprotective agents that show success in animal models of stroke have resulted in very limited clinical success.

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