Evaluation of MR-Derived Cerebral Oxygen Metabolic Index in Experimental Hyperoxic Hypercapnia, Hypoxia, and Ischemia | Zendy

Hongyu An | Zendy; Qingwei Liu | Zendy; Yasheng Chen | Zendy; Weili Lin | Zendy

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Evaluation of MR-Derived Cerebral Oxygen Metabolic Index in Experimental Hyperoxic Hypercapnia, Hypoxia, and Ischemia

Author(s) -

Hongyu An,

Qingwei Liu,

Yasheng Chen,

Weili Lin

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.540864

Subject(s) - medicine , hypercapnia , hypoxia (environmental) , ischemia , cardiology , oxygen , anesthesia , respiratory system , chemistry , organic chemistry

A noninvasive MRI method to measure cerebral oxygen metabolism has the potential to assess tissue viability during cerebral ischemia. The purposes of this study were to validate MR oxygenation measurements across a wide range of global cerebral oxygenation and to examine the spatiotemporal evolution of oxygen metabolism during focal middle cerebral artery occlusion in rats.

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