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We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours poststroke, but the mechanisms are unknown. We now examine effects of candesartan on proangiogenic factors and 7-day outcomes using the same treatment paradigm.

Candesartan Augments Ischemia-Induced Proangiogenic State and Results in Sustained Improvement After Stroke