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To the Editor:We read with interest a recent study by Pilz et al, which reported an association between low levels of 25-hydroxyvitamin D (25-OH D) and an increased risk of fatal stroke.1 In their study, low circulating 25-OH D levels predicted fatal stroke, independent of traditional cerebrovascular risk factors, including age, sex, body mass index, lipid levels, smoking, hypertension and diabetes mellitus. Despite adjustment for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol levels, the …

25-Hydroxyvitamin D and Risk of Stroke: Possible Mediation by Statin Therapy?