Fractalkine Receptor/Ligand Genetic Variants and Carotid Intima-Media Thickness | Zendy

Stéphanie Debette | Zendy; Steve Bevan | Zendy; JeanFrançois Dartigues | Zendy; Matthias Sitzer | Zendy; Matthias Lorenz | Zendy; Pierre Ducimetière | Zendy; Philippe Amouyel | Zendy; Hugh S. Markus | Zendy

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Fractalkine Receptor/Ligand Genetic Variants and Carotid Intima-Media Thickness

Author(s) -

Stéphanie Debette,

Steve Bevan,

JeanFrançois Dartigues,

Matthias Sitzer,

Matthias Lorenz,

Pierre Ducimetière,

Philippe Amouyel,

Hugh S. Markus

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.537159

Subject(s) - cx3cr1 , cx3cl1 , medicine , genetic variants , intima media thickness , common carotid artery , receptor , pathology , genotype , carotid arteries , chemokine , gene , genetics , chemokine receptor , biology

The fractalkine ligand/receptor (CX3CL1/CX3CR1) complex is important in inflammatory responses and has been associated with vascular disease. We determined whether genetic variants in CX3CL1 and CX3CR1 are associated with carotid atherosclerosis in 2 large European populations.

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