Ceruloplasmin/Transferrin System Is Related to Clinical Status in Acute Stroke | Zendy

Claudia Altamura | Zendy; Rosanna Squitti | Zendy; Patrizio Pasqualetti | Zendy; Chiara Gaudino | Zendy; Paola Palazzo | Zendy; Francesco Tibuzzi | Zendy; Domenico Lupoi | Zendy; Maurizio Cortesi | Zendy; Paolo Maria Rossini | Zendy; Fabrizio Vernieri | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Ceruloplasmin/Transferrin System Is Related to Clinical Status in Acute Stroke

Author(s) -

Claudia Altamura,

Rosanna Squitti,

Patrizio Pasqualetti,

Chiara Gaudino,

Paola Palazzo,

Francesco Tibuzzi,

Domenico Lupoi,

Maurizio Cortesi,

Paolo Maria Rossini,

Fabrizio Vernieri

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.536714

Subject(s) - ceruloplasmin , medicine , stroke (engine) , transferrin , ferrous , lesion , superoxide dismutase , hydrogen peroxide , acute stroke , gastroenterology , oxidative stress , surgery , biochemistry , chemistry , materials science , tissue plasminogen activator , engineering , metallurgy , mechanical engineering

In acute stroke, Iron (Fe) may amplify reperfusion injury by catalyzing the conversion of superoxide and hydrogen peroxide into highly reactive radicals. Transferrin (Tf) is the main protein regulating Fe homeostasis, whereas Ceruplasmin (CP) is a circulating ferroxidase enzyme able to oxidize ferrous ions to less toxic ferric forms. This study aims at investigating whether CP, Copper (Cu), Tf, and Fe play a role in the pathophysiology of acute stroke.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research