Cerebrovascular Reactivity Measured by Near-Infrared Spectroscopy | Zendy

Jennifer K. Lee | Zendy; Kathleen K. Kibler | Zendy; Paul Benni | Zendy; R. Blaine Easley | Zendy; Marek Czosnyka | Zendy; Peter Smielewski | Zendy; Raymond C. Koehler | Zendy; Donald H. Shaffner | Zendy; Ken M. Brady | Zendy

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Cerebrovascular Reactivity Measured by Near-Infrared Spectroscopy

Author(s) -

Jennifer K. Lee,

Kathleen K. Kibler,

Paul Benni,

R. Blaine Easley,

Marek Czosnyka,

Peter Smielewski,

Raymond C. Koehler,

Donald H. Shaffner,

Ken M. Brady

Publication year - 2009

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.536094

Subject(s) - medicine , laser doppler velocimetry , blood pressure , cerebral autoregulation , autoregulation , near infrared spectroscopy , spectroscopy , blood volume , doppler effect , nuclear magnetic resonance , blood flow , optics , physics , quantum mechanics , astronomy

The pressure reactivity index (PRx) describes cerebral vessel reactivity by correlation of slow waves of intracranial pressure (ICP) and arterial blood pressure. In theory, slow changes in the relative total hemoglobin (rTHb) measured by near-infrared spectroscopy are caused by the same blood volume changes that cause slow waves of ICP. Our objective was to develop a new index of vascular reactivity, the hemoglobin volume index (HVx), which is a low-frequency correlation of arterial blood pressure and rTHb measured with near-infrared spectroscopy.

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