Inflammation and the Emerging Role of the Toll-Like Receptor System in Acute Brain Ischemia | Zendy

B. J. Marsh | Zendy; Susan L. Stevens | Zendy; Brian Hunter | Zendy; Mary P. StenzelPoore | Zendy

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Inflammation and the Emerging Role of the Toll-Like Receptor System in Acute Brain Ischemia

Author(s) -

B. J. Marsh,

Susan L. Stevens,

Brian Hunter,

Mary P. StenzelPoore

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.534917

Subject(s) - medicine , ischemia , neuroprotection , cpg site , microglia , inflammation , ischemic preconditioning , brain ischemia , stroke (engine) , context (archaeology) , pharmacology , immunology , gene expression , gene , dna methylation , biology , mechanical engineering , paleontology , biochemistry , engineering

Systemic administration of cytosine-guanine (CpG) oligodeoxynucleotides provides neuroprotection against subsequent cerebral ischemic injury. We examined the genomic response of leukocytes and brain cells after ischemia in the context of CpG preconditioning.

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