Open AccessImpact of Monocyte Chemoattractant Protein-1 Deficiency on Cerebral Aneurysm Formation
Author(s) -
Tomohiro Aoki,
Hiroharu Kataoka,
Ryota Ishibashi,
Kazuhiko Nozaki,
Kensuke Egashira,
Nobuo Hashimoto
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.532556
Subject(s) - medicine , monocyte , aneurysm , chemotaxis , cardiology , surgery , receptor
Recent studies have suggested that chronic inflammation actively participates in cerebral aneurysm (CA) formation. Macrophages accumulate in CA walls and express proinflammatory genes promoting CA progression, but the molecular mechanisms of monocyte/macrophage recruitment into CA walls remain to be elucidated.
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