Ultrasound-Enhanced Thrombolysis: From Bedside to Bench | Zendy

Jürgen Eggers | Zendy

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Ultrasound-Enhanced Thrombolysis: From Bedside to Bench

Author(s) -

Jürgen Eggers

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.531848

Subject(s) - medicine , thrombolysis , intracerebral hemorrhage , occlusion , transcranial doppler , ultrasound , recombinant tissue plasminogen activator , subarachnoid hemorrhage , surgery , radiology , ischemic stroke , cardiology , ischemia , modified rankin scale , myocardial infarction

To the Editor:We highly appreciate Tsivgoulis and Alexandrov’s1 comment regarding our article about sonothrombolysis with transcranial color-coded sonography (TCCS) and recombinant tissue plasminogen activator.2 However, several conclusions made by these colleagues require a response. The assumption that the multibeam configuration of TCCS causes an increased rate of symptomatic intracranial hemorrhage in the target group is not justified. The overwhelming part of insonation was performed by using the pulsed wave Doppler mode as it was also used by Alexandrov and coworkers in the CLOTBUST trial.3 As we …

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