Thrombin Inhibition by Argatroban Ameliorates Early Brain Injury and Improves Neurological Outcomes After Experimental Subarachnoid Hemorrhage in Rats
Author(s) -
Takashi Sugawara,
Vikram Jadhav,
Robert Ayer,
Wanqiu Chen,
Hidenori Suzuki,
John H. Zhang
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.531699
Subject(s) - argatroban , medicine , subarachnoid hemorrhage , neuroprotection , thrombin , pharmacology , anesthesia , blood–brain barrier , intracerebral hemorrhage , discovery and development of direct thrombin inhibitors , central nervous system , platelet
We investigated the role of thrombin in early brain injury after subarachnoid hemorrhage (SAH).
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