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Pharmacogenomic Effects of Apolipoprotein E on Intracerebral Hemorrhage
Author(s) -
Michael L. James,
Patrick M. Sullivan,
Christopher D. Lascola,
Michael P. Vitek,
Daniel T. Laskowitz
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.530402
Subject(s) - medicine , intracerebral hemorrhage , apolipoprotein e , apolipoprotein b , anesthesia , edema , nitric oxide synthase , endocrinology , nitric oxide , subarachnoid hemorrhage , pathology , disease , cholesterol
The purpose of the study was to evaluate the effect of APOE genotype and the feasibility of administering an apolipoprotein E-mimetic therapeutic to modify outcomes in a murine model of intracerebral hemorrhage.

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