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Development of a Rat Model of Photothrombotic Ischemia and Infarction Within the Caudoputamen
Author(s) -
Toshihiko Kuroiwa,
Guohua Xi,
Ya Hua,
Tavarekere N. Nagaraja,
Joseph D. Fenstermacher,
Richard F. Keep
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.527853
Subject(s) - medicine , ischemia , cardiology , infarction , stroke (engine) , ischemic stroke , cerebral infarction , myocardial infarction , mechanical engineering , engineering
Basal ganglia infarction is typically caused by the occlusion of deep arteries and the formation of relatively small lesions called lacunes. In the present study, a rat model of lacunar infarction was induced by photothrombotic occlusion of the small vessels within the caudate-putamen and subsequently characterized.

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