MRI Identification of White Matter Reorganization Enhanced by Erythropoietin Treatment in a Rat Model of Focal Ischemia
Author(s) -
Lian Li,
Quan Jiang,
Guangliang Ding,
Li Zhang,
Zheng Gang Zhang,
Qingjiang Li,
Swayamprava Panda,
Alissa Kapke,
Mei Lü,
James R. Ewing,
Michael Chopp
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.527713
Subject(s) - white matter , fractional anisotropy , medicine , erythropoietin , ischemia , cerebral blood flow , diffusion mri , stroke (engine) , magnetic resonance imaging , pathology , anesthesia , radiology , mechanical engineering , engineering
The objectives of the present study were to: (1) noninvasively identify white matter reorganization and monitor its progress within 6 weeks after the onset of stroke; and (2) quantitatively investigate the effect of recombinant human erythropoietin treatment on this structural change using in vivo measurement of diffusion anisotropy.
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