Open AccessApoptotic Functions of PDCD10/CCM3 , the Gene Mutated in Cerebral Cavernous Malformation 3
Author(s) -
Leiling Chen,
Gamze Tanrıöver,
Hiroko Yano,
Robert M. Friedlander,
Angeliki Louvi,
Murat Günel
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.527135
Subject(s) - apoptosis , programmed cell death , tunel assay , gene knockdown , microbiology and biotechnology , medicine , biology , cancer research , genetics
Mutations in the Programmed Cell Death 10 (PDCD10) gene cause autosomal dominant familial cerebral cavernous malformations (CCM3). To date, little is known about the function of this gene and its role in disease pathogenesis.
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