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Effect of Age on Stroke Prevention Therapy in Patients With Atrial Fibrillation
Author(s) -
Carl van Walraven,
Robert G. Hart,
Stuart J. Connolly,
Peter C. Austin,
Jonathan Mant,
Richard Hobbs,
Peter J. Koudstaal,
Palle Petersen,
Francisco Pérez-Gómez,
J. André Knottnerus,
B. S. P. Boode,
Michael D. Ezekowitz,
Daniel E. Singer
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.526988
Subject(s) - medicine , atrial fibrillation , stroke (engine) , cardiology , ischemic stroke , ischemia , mechanical engineering , engineering
Stroke risk increases with age in patients who have nonvalvular atrial fibrillation. It is uncertain whether the efficacy of stroke prevention therapies in atrial fibrillation changes as patients age. The objective of this study was to determine the effect of age on the relative efficacy of oral anticoagulants (OAC) and antiplatelet (AP) therapy (including acetylsalicylic acid and triflusal) on ischemic stroke, serious bleeding, and vascular events in patients with atrial fibrillation.

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