High-Dose B Vitamin Supplementation and Progression of Subclinical Atherosclerosis
Author(s) -
Howard N. Hodis,
Wendy J. Mack,
Laurie Dustin,
Peter R. Mahrer,
Stanley P. Azen,
Robert Detrano,
Jacob Selhub,
Petar Alaupovic,
Chaoran Liu,
Liu Ci-hua,
Juliana Hwang,
Alison Wilcox,
Robert H. Selzer
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.526798
Subject(s) - medicine , homocysteine , placebo , subclinical infection , vitamin d and neurology , gastroenterology , intima media thickness , coronary artery disease , cardiology , vascular disease , vitamin , b vitamins , endocrinology , pathology , carotid arteries , alternative medicine
Although plasma total homocysteine (tHcy) levels are associated with cardiovascular disease, it remains unclear whether homocysteine is a cause or a marker of atherosclerotic vascular disease. We determined whether reduction of tHcy levels with B vitamin supplementation reduces subclinical atherosclerosis progression.
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