Lithium Upregulates Vascular Endothelial Growth Factor in Brain Endothelial Cells and Astrocytes
Author(s) -
Shuzhen Guo,
Ken Arai,
Monique F. Stins,
DeMaw Chuang,
Eng H. Lo
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.524504
Subject(s) - vascular endothelial growth factor , endocrinology , astrocyte , lithium (medication) , medicine , neurotrophic factors , vascular endothelial growth factor a , signal transduction , microbiology and biotechnology , biology , central nervous system , receptor , vegf receptors
We recently reported that delayed lithium therapy can improve stroke recovery in rats by augmenting neurovascular remodeling. We tested the hypothesis that lithium can promote the expression of growth factors in brain endothelial cells and astrocytes.
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