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Serial Diffusion Imaging in a Case of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes
Author(s) -
Charalampos Tzoulis,
Laurence A. Bindoff
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.523118
Subject(s) - mitochondrial encephalomyopathy , lactic acidosis , medicine , stroke (engine) , melas syndrome , effective diffusion coefficient , cardiology , lesion , acidosis , mitochondrial myopathy , pathology , magnetic resonance imaging , mitochondrial dna , radiology , biology , genetics , mechanical engineering , gene , engineering
Most diffusion MRI studies of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episode stroke-like lesions report high- or normal-apparent diffusion coefficient, and this has been used to differentiate stroke-like lesion from ischemic stroke. There are, however, 3 recent reports of restricted diffusion in the acute phase of the stroke-like lesions. The purpose of our study was to investigate this apparent paradox.

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