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Ultrafast High-Resolution In Vivo Volume-CTA of Mice Cerebral Vessels
Author(s) -
Sebastian J. Schambach,
Simona Bag,
Volker Steil,
Cristina T. Isaza,
Lothar Schilling,
Christoph Groden,
Marc A. Brockmann
Publication year - 2009
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.521740
Subject(s) - medicine , in vivo , iodinated contrast , biomedical engineering , nuclear medicine , angiography , voxel , radiology , pathology , computed tomography , microbiology and biotechnology , biology
Animal models developed in rats and mice have become indispensable in preclinical cerebrovascular research. Points of interest include the investigation of the vascular bed and the morphology and function of the arterial, capillary, and venous vessels. Because of their extremely small caliber, in vivo examination of these vessels is extremely difficult. In the present study we have developed a method to provide fast 3D in vivo analysis of cerebral murine vessels using volume computed tomography-angiography (vCTA).

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