The Presence of a Right-to-Left Shunt Is Associated With Dramatic Improvement After Thrombolytic Therapy in Patients With Acute Ischemic Stroke | Zendy

Kazumi Kimura | Zendy; Yasuyuki Iguchi | Zendy; Kensaku Shibazaki | Zendy; Yuka Terasawa | Zendy; Junya Aoki | Zendy; Noriko Matsumoto | Zendy

Open Access

The Presence of a Right-to-Left Shunt Is Associated With Dramatic Improvement After Thrombolytic Therapy in Patients With Acute Ischemic Stroke

Author(s) -

Kazumi Kimura,

Yasuyuki Iguchi,

Kensaku Shibazaki,

Yuka Terasawa,

Junya Aoki,

Noriko Matsumoto

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.521146

Subject(s) - medicine , thrombolysis , stroke (engine) , transcranial doppler , tissue plasminogen activator , thrombus , cardiology , atrial fibrillation , modified rankin scale , fibrinolytic agent , univariate analysis , intracerebral hemorrhage , prospective cohort study , surgery , multivariate analysis , ischemia , ischemic stroke , myocardial infarction , mechanical engineering , subarachnoid hemorrhage , engineering

The efficacy of pharmacological thrombolysis using tissue plasminogen activator depends on the relative fibrin content of the thrombus. We investigated whether patients with stroke with a right-to-left shunt (RLS), whose embolic source was associated with fibrin-rich thrombus formed in the venous system, were more likely to improve dramatically after thrombolytic therapy than those without RLS.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research