Effect of Raloxifene on Stroke and Venous Thromboembolism According to Subgroups in Postmenopausal Women at Increased Risk of Coronary Heart Disease
Author(s) -
Lori Mosca,
Deborah Grady,
Elizabeth BarrettConnor,
Peter Collins,
Nanette K. Wenger,
Beth L. Abramson,
Annlia PaganiniHill,
Mary Jane Geiger,
Sherie A. Dowsett,
Messan G. Amewou-Atisso,
Marcel Kornitzer
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.518621
Subject(s) - raloxifene , medicine , stroke (engine) , placebo , incidence (geometry) , selective estrogen receptor modulator , osteoporosis , venous thromboembolism , cardiology , breast cancer , estrogen receptor , cancer , thrombosis , pathology , mechanical engineering , physics , alternative medicine , optics , engineering
Raloxifene, a selective estrogen receptor modulator, reduces risk of invasive breast cancer and osteoporosis, but the effect on risk for stroke and venous thromboembolism in different patient subgroups is not established. The purpose of this analysis was to evaluate the effect of raloxifene on the incidence of all strokes, stroke deaths, and venous thromboembolic events according to participant subgroups.
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