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Atorvastatin Reduces the Risk of Cardiovascular Events in Patients With Carotid Atherosclerosis
Author(s) -
Henrik Sillesen,
Pierre Amarenco,
Michael G. Hennerici,
Alfred Callahan,
Larry B. Goldstein,
Justin A. Zivin,
Michael Messig,
K.M.A. Welch
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.108.516450
Subject(s) - medicine , atorvastatin , stroke (engine) , stenosis , cardiology , hazard ratio , myocardial infarction , population , randomized controlled trial , confidence interval , environmental health , mechanical engineering , engineering
The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial found that treatment with atorvastatin 80 mg per day reduced the risk of stroke and cardiovascular events in patients with a recent transient ischemic attack (TIA) or stroke. We hypothesized this benefit would be greatest in the subgroup of patients with carotid stenosis.

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