Protecting Against Cerebrovascular Injury | Zendy

Guang Jin | Zendy; Ken Arai | Zendy; Yoshihiro Murata | Zendy; Sophia Y. Wang | Zendy; Monique F. Stins | Zendy; Eng H. Lo | Zendy; Klaus van Leyen | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Protecting Against Cerebrovascular Injury

Author(s) -

Guang Jin,

Ken Arai,

Yoshihiro Murata,

Sophia Y. Wang,

Monique F. Stins,

Eng H. Lo,

Klaus van Leyen

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.108.514927

Subject(s) - medicine , stroke (engine) , medical emergency , mechanical engineering , engineering

The concept of the neurovascular unit suggests that effects on brain vasculature must be considered if neuroprotection is to be achieved in stroke. We previously reported that 12/15-lipoxygenase (12/15-LOX) is upregulated in the peri-infarct area after middle cerebral artery occlusion in mice, and 12/15-LOX contributes to brain damage after ischemia-reperfusion. The current study was designed to investigate 12/15-LOX involvement in vascular injury in the ischemic brain.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research