Statins and Secondary Prevention of Ischemic and Hemorrhagic Stroke | Zendy

Alessandro Squizzato | Zendy; Francesco Dentali | Zendy; Erica Romualdi | Zendy; Walter Ageno | Zendy

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Statins and Secondary Prevention of Ischemic and Hemorrhagic Stroke

Author(s) -

Alessandro Squizzato,

Francesco Dentali,

Erica Romualdi,

Walter Ageno

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.517151

Subject(s) - medicine , stroke (engine) , secondary prevention , ischemic stroke , emergency medicine , surgery , ischemia , mechanical engineering , engineering

To the Editor:Identification of patients who benefit from statin treatment after an acute cerebrovascular event is still a matter of debate. The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study was designed to address this question, and it showed that statins exert a marginally beneficial effect on stroke prevention in patients with a history of ischemic stroke, transient ischemic attack, or hemorrhagic stroke.1 Moreover, an increased occurrence of hemorrhagic stroke in patients on statins treatment was observed, in particular in patients with a history of hemorrhagic stroke. To confirm SPARCL data, Vergouwen and colleagues performed a systematic review focused on the effect of statin treatment on the occurrence of ischemic and …

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