Cathepsin B, K, and S Are Expressed in Cerebral Aneurysms and Promote the Progression of Cerebral Aneurysms | Zendy

Tomohiro Aoki | Zendy; Hiroharu Kataoka | Zendy; Ryota Ishibashi | Zendy; Kazuhiko Nozaki | Zendy; Nobuo Hashimoto | Zendy

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Cathepsin B, K, and S Are Expressed in Cerebral Aneurysms and Promote the Progression of Cerebral Aneurysms

Author(s) -

Tomohiro Aoki,

Hiroharu Kataoka,

Ryota Ishibashi,

Kazuhiko Nozaki,

Nobuo Hashimoto

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.513648

Subject(s) - cathepsin , cystatin , cathepsin s , elastin , cathepsin b , cathepsin h , cystatin c , medicine , cysteine , extracellular matrix , immunohistochemistry , cathepsin k , cathepsin l , cathepsin a , pathology , microbiology and biotechnology , biochemistry , biology , endocrinology , enzyme , renal function , receptor , osteoclast

A cerebral aneurysm (CA) causes catastrophic subarachnoid hemorrhage. Degradation of extracellular matrix in arterial walls is a prominent feature of cerebral aneurysms. We investigated the expression and role of cysteine cathepsins, collagen- and elastin- degrading proteinases, in CA progression.

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