Lipoprotein-Associated Phospholipase A 2 and High-Sensitivity C-Reactive Protein Improve the Stratification of Ischemic Stroke Risk in the Atherosclerosis Risk in Communities (ARIC) Study | Zendy

Vijay Nambi | Zendy; Ron C. Hoogeveen | Zendy; Lloyd E. Chambless | Zendy; YiJuan Hu | Zendy; Heejung Bang | Zendy; Josef Coresh | Zendy; Hanyu Ni | Zendy; Eric Boerwinkle | Zendy; Thomas H. Mosley | Zendy; Richey Sharrett | Zendy; Aaron R. Folsom | Zendy; Christie M. Ballantyne | Zendy

Open Access

Lipoprotein-Associated Phospholipase A ₂ and High-Sensitivity C-Reactive Protein Improve the Stratification of Ischemic Stroke Risk in the Atherosclerosis Risk in Communities (ARIC) Study

Author(s) -

Vijay Nambi,

Ron C. Hoogeveen,

Lloyd E. Chambless,

YiJuan Hu,

Heejung Bang,

Josef Coresh,

Hanyu Ni,

Eric Boerwinkle,

Thomas H. Mosley,

Richey Sharrett,

Aaron R. Folsom,

Christie M. Ballantyne

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.513259

Subject(s) - medicine , lipoprotein associated phospholipase a2 , c reactive protein , lipoprotein(a) , stroke (engine) , prospective cohort study , risk factor , receiver operating characteristic , lipoprotein , gastroenterology , inflammation , cholesterol , mechanical engineering , engineering

Inflammation plays a critical role in the development of vascular disease, and increased levels of the inflammatory biomarkers, lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), and high-sensitivity C-reactive protein (hs-CRP) have been shown to be associated with an increased risk for ischemic stroke.

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