Plasma Levels of Vascular Endothelial Growth Factor After Treatment for Cerebral Arteriovenous Malformations
Author(s) -
Grace H. Kim,
David Hahn,
Christopher P. Kellner,
Zachary L. Hickman,
Ricardo J. Komotar,
Robert M. Starke,
William J. Mack,
J Mocco,
Robert A. Solomon,
E. Sander Connolly
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.512442
Subject(s) - medicine , vascular endothelial growth factor , pathophysiology , arteriovenous malformation , angiogenesis , vegf receptors , gastroenterology , endocrinology , urology , pathology , surgery
The role of abnormal angiogenesis in the formation and progression of cerebral arteriovenous malformations (AVMs) is unclear. Previous studies have demonstrated increased local expression of vascular endothelial growth factor (VEGF) in AVM tissue and increased circulating levels of VEGF in AVM patients. We sought to further investigate the role of VEGF in AVM pathophysiology by examining changes in plasma VEGF levels in patients undergoing treatment for AVMs.
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