Diagnostic Accuracy of Magnetic Resonance Angiography for Internal Carotid Artery Disease | Zendy

Sarah M. Debrey | Zendy; Hua Yu | Zendy; J.A. Lynch | Zendy; KarlOlof Lövblad | Zendy; Violet Wright | Zendy; SokJa Janket | Zendy; Alison E. Baird | Zendy

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Diagnostic Accuracy of Magnetic Resonance Angiography for Internal Carotid Artery Disease

Author(s) -

Sarah M. Debrey,

Hua Yu,

J.A. Lynch,

KarlOlof Lövblad,

Violet Wright,

SokJa Janket,

Alison E. Baird

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.509877

Subject(s) - medicine , internal carotid artery , magnetic resonance angiography , gold standard (test) , radiology , stenosis , angiography , stroke (engine) , magnetic resonance imaging , nuclear medicine , mechanical engineering , engineering

Accurate diagnosis of the degree of internal carotid artery (ICA) stenosis is needed for decisions regarding optimal stroke prevention. Noninvasive magnetic resonance angiography (MRA) is being proposed and used as a replacement for the gold standard, intra-arterial angiography. Our purpose was to perform a systematic review and diagnostic meta-analysis to determine the sensitivity and specificity of time-of-flight (TOF) MRA and contrast-enhanced (CE) MRA for the detection of (1) high-grade (> or = 70% to 99%) ICA stenoses; (2) ICA occlusions; (3) moderately severe (50% to 69%) ICA stenoses; and (4) compare the overall accuracy of the 2 MRA techniques.

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