Effects of Thrombin on Neurogenesis After Intracerebral Hemorrhage
Author(s) -
Shuxu Yang,
Shuijiang Song,
Ya Hua,
Takehiro Nakamura,
Richard F. Keep,
Guohua Xi
Publication year - 2008
Publication title -
stroke
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.397
H-Index - 319
eISSN - 1524-4628
pISSN - 0039-2499
DOI - 10.1161/strokeaha.107.508911
Subject(s) - neurogenesis , doublecortin , thrombin , medicine , intracerebral hemorrhage , hirudin , endocrinology , immunohistochemistry , subventricular zone , basal ganglia , dentate gyrus , hippocampus , neuroscience , neural stem cell , central nervous system , biology , microbiology and biotechnology , platelet , stem cell , subarachnoid hemorrhage
Neurogenesis in intracerebral hemorrhage (ICH) has not been investigated. Thrombin formation causes acute brain injury after ICH, but thrombin also can stimulate cell proliferation. The present study examined whether neurogenesis takes place in ICH and the role of thrombin in ICH-related neurogenesis.
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