DP-b99, a Membrane-Activated Metal Ion Chelator, as Neuroprotective Therapy in Ischemic Stroke | Zendy

HansChristoph Diener | Zendy; Dietmar Schneider | Zendy; Yair Lampl | Zendy; Natan M. Bornstein | Zendy; Alexander Kozak | Zendy; G Rosenberg | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

DP-b99, a Membrane-Activated Metal Ion Chelator, as Neuroprotective Therapy in Ischemic Stroke

Author(s) -

HansChristoph Diener,

Dietmar Schneider,

Yair Lampl,

Natan M. Bornstein,

Alexander Kozak,

G Rosenberg

Publication year - 2008

Publication title -

stroke

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.397

H-Index - 319

eISSN - 1524-4628

pISSN - 0039-2499

DOI - 10.1161/strokeaha.107.506378

Subject(s) - medicine , placebo , modified rankin scale , stroke (engine) , neuroprotection , adverse effect , randomized controlled trial , clinical trial , cohort , anesthesia , surgery , ischemia , ischemic stroke , pathology , mechanical engineering , alternative medicine , engineering

DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke. We present the results of a multicenter, double-blind, placebo-controlled, randomized trial to assess the safety and potential protective effects of DP-b99 in acute ischemic stroke.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research